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Autoimmune Disease

www.ebooks.com/cj.asp?IID=1399076&cjsku=1399076...
This book describes how the Jerne-Burnet Forbidden Clone Theory and the Adams-Knight H Gene Theory, solved the pathogenesis and genetics of the autoimmune diseases showing how specific immunotherapy and prophylaxis can be developed. Furthermore, Ebringer's discovery of two microbial triggers of autoimmune diseases is described and the conclusion drawn that all autoimmune diseases have microbial triggers, so will be preventable by the finding of the triggers and vaccination against them.
Category: Medicine. ISBN: 9789400769366

Autoimmunity and Autoimmune Disease

www.ebooks.com/cj.asp?IID=470679&cjsku=470679...
This work focuses on the autoimmune processes that have now been proven to underlie a number of serious diseases, including diabetes mellitus, rheumatoid arthritis and multiple sclerosis. Papers explore the rapidly expanding developments in research on immune response and regulation, and their potential in the development of treatments for autoimmune diseases. The wide range of subjects covered here include: the nature of intracellular and cell surface-derived ``self'' antigens; competing theories of the generation of immune tolerance and their implications of current theories for research and treatment; possible links between autoimmunity and genetic complement deficiency; the contributions of interferons and class II HLA antigen expression to autoimmunity; and the potential of monoclonal antibodies and other biotechnological advances in treating human autoimmune conditions.
Category: Medicine. ISBN: 9780471910954

Autoimmune Disease Models

www.ebooks.com/cj.asp?IID=1675845&cjsku=1675845...
Because autoimmune disorders can wreak havoc in both humans and animals, these disorders are now the objects of intense and focused research. This book details specific animal models for a variety of autoimmune disorders. The contributors are recognized authorities who deal with the panoply of experimentally induced autoimmune disorders, including encephalomyelitis, allergic neuritis, uveoretinitis, myocarditis, and hepatitis. Also included are discussions of spontaneously appearing diseases such as autoimmune thyroiditis and systemic lupus erythematosus. Many other disorders are also covered in this comprehensive guide. Certain to be an aid in the planning of individual experiments and broader research programs, this book will be a valuable addition to the library of all practicing immunologists interested in immune system function and dysfunction.
Category: Health & Fitness. ISBN: 9780121783303

Immunogenetics of Autoimmune Disease

www.ebooks.com/cj.asp?IID=338028&cjsku=338028...
utoimmunity is the downstream outcome of a rather extensive and coordinated series of events that include loss of self-tolerance, peripheral lymphocyte Aactivation, disruption of the blood-systems barriers, cellular infiltration into the target organs and local inflammation. Cytokines, adhesion molecules, growth factors, antibodies, and other molecules induce and regulate critical cell functions that perpetuate inflammation, leading to tissue injury and clinical phenotype. The nature and intensity of this response as well as the physiological ability to restore homeostasis are to a large extent conditioned by the unique amino acid sequences that define allelic variants on each of the numerous participating mol ecules. Therefore, the coding genes in their germline configuration play a primary role in determining who is at risk for developing such disorders, how the disease progresses, and how someone responds to therapy. Although genetic components in these diseases are clearly present, the lack of obvious and homogeneous modes of transmission has slowed progress by prevent ing the full exploitation of classical genetic epidemiologic techniques. Furthermore, autoimmune diseases are characterized by modest disease risk heritability and m- tifaceted interactions with environmental influences. Yet, several recent discoveries have dramatically changed our ability to examine genetic variation as it relates to human disease. In addition to the development of large-scale laboratory methods and tools to efficiently recognize and catalog DNA diversity, over the past few years there has been real progress in the application of new analytical and data-manage ment approaches.
Category: Science. ISBN: 9780387360041

Autoimmune Neurological Disease

www.ebooks.com/cj.asp?IID=638320&cjsku=638320...
This book reviews autoimmune neurological disease, including such common conditions as multiple sclerosis, the Guillain Barre syndrome and myasthenia gravis.
Category: Medicine. ISBN: 9780521461139

CTLA-4 in Autoimmune Disease

www.ebooks.com/cj.asp?IID=226248&cjsku=226248...
Table of Contents CTLA-4 in Systemic Lupus Erythematosus David Wofsky CTLA-4 in Rheumatoid Arthritis Marc Feldmann CTLA-4 in Vitiligo E. Helen Kemp CTLA-4 in Myastenia Gravis Ann Kari Lefvert CTLA-4 in Multiple Sclerosis Arlene H. Sharpe CTLA-4 in Addison's Disease Klaus Badenhoop CTLA-4 in Type 1 Diabetes Paulo Pozzilli CTLA-4 in Thyroid Autoimmune Disorders Anthony P. Weetman
Category: Medicine. ISBN: 9781587060687

Epigenetic Contributions in Autoimmune Disease

www.ebooks.com/cj.asp?IID=799079&cjsku=799079...
This volume focuses on the relevance of epigenetic mechanisms in autoimmune disease. It provides new directions for future research in autoimmune disease.
Category: Medicine. ISBN: 9781441982155

Living Well with Autoimmune Disease

www.ebooks.com/cj.asp?IID=293897&cjsku=293897...
A complete guide to understanding the mysterious and often difficult-to-pinpoint disorders of the immune system--and finding the keys to diagnosis, treatment, and recovery. An estimated fifty million people suffer from symptoms including fatigue, joint pains, depression, or heart palpitations signs that the immune system has turned on itself, causing conditions such as thyroid disease, hepatitis, or multiple sclerosis. And while doctors may prescribe treatments to relieve these surface ailments, when asked about the life-long health implications of an autoimmune condition, they often just shrug their shoulders. Yet much like cancer, having one autoimmune disease puts you at high risk for developing another, and understanding the underlying immune process can reverse a patients approach to a dysfunction--for the author, it changed the way she ate, the vitamins and supplements she took, and the types of doctors she visited. Living Well with Autoimmune Disease is the first book that goes beyond the conventional treatments by showing you how to work on your underlying autoimmune dysfunction with natural and alternative therapies.
Category: Family & Relationships. ISBN: 9780060938192

Gene Therapy of Autoimmune Disease

www.ebooks.com/cj.asp?IID=323630&cjsku=323630...
Autoimmune diseases are diverse and responsible for considerable morbidity. Their etiology remains largely unknown, and current therapy with anti-inflammatory drugs is prone to adverse effects, and rarely curative. New therapies with anti-cytokine antibodies or receptors are promising, but require frequent administration of expensive protein drugs. Gene Therapy of Autoimmune Diseases comprehensively reviews research in gene therapy for autoimmune diseases with viral or non-viral vectors. Gene therapy offers the possibility of long-term, continuous delivery of a wide variety of immunosuppressive, anti-inflammatory, or tolerance-inducing agents. Moreover, highly specific genetically modified cells can be produced. This book discusses the most promising avenues in this exciting new field.
Category: Health & Fitness. ISBN: 9780306479915

Women, Work, and Autoimmune Disease

www.ebooks.com/cj.asp?IID=2266466&cjsku=2266466...
Women, Work, and Autoimmune Disease is a book for women who live with chronic illness, encouraging them to stay employed to preserve their independence and sense of self. Rich with information and inspiration, it is the voice of warmth, wisdom, understanding, and compassion. Filled with tips, tricks and first-person accounts from women who have made similar choices in their own lives, this unique book is a resounding call for self-reliance and resilience. The book identifies the factors that making working particularly difficult for women with autoimmune disease, and then offers practical suggestions to address them. The authors take a hard, yet inspirational look at what it takes be successful in a job, including developing strategies and tactics, evaluating communication skills, building a support team and considerations for self-employment. Women, Work, and Autoimmune Disease covers issues such as: The complex nature of autoimmune disease The correlation between disease, diagnosis, and career development How life-changing strategies and concrete tactics can allow you to discover the spirit within
Category: Health & Fitness. ISBN: 9781932603682
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