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March's Advanced Organic Chemistry
The new, revised and updated 7 th edition of March’s Advanced Organic Chemistry clearly explains the theories and examples of organic chemistry, providing the most comprehensive resource about organic chemistry available. Readers are guided on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions. The first five chapters deal with the structure of organic compounds and discuss important organic chemistry bonds, fundamental principles of conformation, and stereochemistry of organic molecules, and reactive intermediates in organic chemistry. Chapters 6 to 9 are concerned with general principles of mechanism in organic chemistry, including acids and bases, photochemistry, sonochemistry and microwave irradiation, and finally the relationship between structure and reactivity. The last 10 chapters cover the nature and the scope of organic reactions and their mechanisms. The 7 th edition proves again it is a must-have desktop reference and textbook for every student and professional working in organic chemistry or related fields. Key features of the 7 th edition: Every chapter has been updated with the most recent reaction information with references to both the primary and review literature New to the 7th edition: 5,500 references since the last edition, updates / rewrites of the retained sections, and an updated index in Appendix B Contains more than 1650 reactions and 20,000 valuable references to the primary literature Includes appendices on the literature of organic chemistry and the classification of reactions according to the compounds synthesized Guides the reader on planning and execution of multi-step synthetic reactions, with detailed descriptions of all the reactions.  Reviews of the previous edition: "...a favorite general organic chemistry text and an easy-to-use one-volume reference. We are confident that this book will remain a dominant reference and that it will reside on many chemists' personal bookshelves." – Journal of Medicinal Chemistry "Who can hope to be seriously accepted as a member of the organic chemistry community without being in possession of at least one edition of 'March'?" – Chemistry and Industry
Category: Science. ISBN: 9780470462591

Advanced Organic Chemistry
Since its original appearance in 1977, Advanced Organic Chemistry has found wide use as a text providing broad coverage of the structure, reactivity and synthesis of organic compounds. The Fourth Edition provides updated material but continues the essential elements of the previous edition. The material in Part A is organized on the basis of fundamental structural topics such as structure, stereochemistry, conformation and aromaticity and basic mechanistic types, including nucleophilic substitution, addition reactions, carbonyl chemistry, aromatic substitution and free radical reactions. The material in Part B is organized on the basis of reaction type with emphasis on reactions of importance in laboratory synthesis. As in the earlier editions, the text contains extensive references to both the primary and review literature and provides examples of data and reactions that illustrate and document the generalizations. While the text assumes completion of an introductory course in organic chemistry, it reviews the fundamental concepts for each topic that is discussed. The Fourth Edition updates certain topics that have advanced rapidly in the decade since the Third Edition was published, including computational chemistry, structural manifestations of aromaticity, enantioselective reactions and lanthanide catalysis. The two parts stand alone, although there is considerable cross-referencing. Part A emphasizes quantitative and qualitative description of structural effects on reactivity and mechanism. Part B emphasizes the most general and useful synthetic reactions. The focus is on the core of organic chemistry, but the information provided forms the foundation for future study and research in medicinal and pharmaceutical chemistry, biological chemistry and physical properties of organic compounds. The New Revised 5th Edition will be available shortly. For details, click on the link in the right-hand column.
Category: Science. ISBN: 9780306462429

Intermediate Organic Chemistry
This book presents key aspects of organic synthesis – stereochemistry, functional group transformations, bond formation, synthesis planning, mechanisms, and spectroscopy – and a guide to literature searching in a reader-friendly manner. •    Helps students understand the skills and basics they need to move from introductory to graduate organic chemistry classes •    Balances synthetic and physical organic chemistry in a way accessible to students •    Features extensive end-of-chapter problems •    Updates include new examples and discussion of online resources now common for literature searches •    Adds sections on protecting groups and green chemistry along with a rewritten chapter surveying organic spectroscopy
Category: Science. ISBN: 9781118308813

Experimental Organic Chemistry
The definitive guide to the principles and practice of experimental organic chemistry - fully updated and now featuring more than 100 experiments The latest edition of this popular guide to experimental organic chemistry takes students from their first day in the laboratory right through to complex research procedures. All sections have been updated to reflect new techniques, equipment and technologies, and the text has been revised with an even sharper focus on practical skills and procedures. The first half of the book is devoted to safe laboratory practice as well as purification and analytical techniques; particularly spectroscopic analysis. The second half contains step-by-step experimental procedures, each one illustrating a basic principle, or important reaction type. Tried and tested over almost three decades, over 100 validated experiments are graded according to their complexity and all are chosen to highlight important chemical transformations and to teach key experimental skills. New sections cover updated health and safety guidelines, additional spectroscopic techniques, electronic notebooks and record keeping, and techniques, such as semi-automated chromatography and enabling technologies such as the use of microwave and flow chemistry. New experiments include transition metal-catalysed cross-coupling, organocatalysis, asymmetric synthesis, flow chemistry, and microwave-assisted synthesis. Key aspects of this third edition include: Detailed descriptions of the correct use of common apparatus used in the organic laboratory Outlines of practical skills that all chemistry students must learn Highlights of aspects of health and safety in the laboratory, both in the first section and throughout the experimental procedures Four new sections reflecting advances in techniques and technologies, from electronic databases and information retrieval to semi-automated chromatography More than 100 validated experiments of graded complexity from introductory to research level A user-friendly experiment directory An instructor manual and PowerPoint slides of the figures in the book available on a companion website A comprehensive guide to contemporary organic chemistry laboratory principles, procedures, protocols, tools and techniques,  Experimental Organic Chemistry, Third Edition  is both an essential laboratory textbook for students of chemistry at all levels, and a handy bench reference for experienced chemists. 
Category: Science. ISBN: 9781119952381

Theoretical Organic Chemistry
This volume is devoted to the various aspects of theoretical organic chemistry. In the nineteenth century, organic chemistry was primarily an experimental, empirical science. Throughout the twentieth century, the emphasis has been continually shifting to a more theoretical approach. Today, theoretical organic chemistry is a distinct area of research, with strong links to theoretical physical chemistry, quantum chemistry, computational chemistry, and physical organic chemistry. The objective in this volume has been to provide a cross-section of a number of interesting topics in theoretical organic chemistry, starting with a detailed account of the historical development of this discipline and including topics devoted to quantum chemistry, physical properties of organic compounds, their reactivity, their biological activity, and their excited-state properties.
Category: Science. ISBN: 9780444826602

Advanced Organic Chemistry
of Part A.- 1. Chemical Bonding and Molecular Structure.- 1.1. Valence-Bond Approach to Chemical Bonding.- 1.2. Bond Energies, Lengths, and Dipoles.- 1.3. Molecular Orbital Theory.- 1.4. Hckel Molecular Orbital Theory.- General References.- Problems.- 2. Stereochemical Principles.- 2.1. Enantiomeric Relationships.- 2.2. Diastereomeric Relationships.- 2.3. Dynamic Stereochemistry.- 2.4. Prochiral Relationships.- General References.- Problems.- 3. Conformational and Other Steric Effects.- 3.1. Steric Strain and Molecular Mechanics.- 3.2. Conformations of Acyclic Molecules.- 3.3. Conformations of Cyclohexane Derivatives.- 3.4. Carbocyclic Rings Other Than Six-Membered.- 3.5. Heterocyclic Conformational Analysis.- 3.6. Molecular Orbital Methods Applied to Conformational Analysis.- 3.7. Conformational Effects on Reactivity.- 3.8. Other Steric Effects on Reactivity.- General References.- Problems.- 4. Study and Description of Organic Reaction Mechanisms.- 4.1. Thermodynamic Data.- 4.2. Kinetic Data.- 4.3. Substituent Effects and Linear Free-Energy Relationships.- 4.4. Isotope Effects.- 4.5. Characterization of Reaction Intermediates.- 4.6. Catalysis.- 4.7. Solvent Effects.- 4.8.Basic Mechanistic Concepts: Kinetic Versus Thermodynamic Control, Hammond's Postulate, the Curtin-Hammett Principle.- 4.9. Isotopes in Labeling Experiments.- 4.10. Stereochemistry.- General References.- Problems.- 5. Nucleophilic Substitution.- 5.1. The Limiting CasesSubstitution by the Ionization (SN1) Mechanism.- 5.2. The Limiting CasesSubstitution by the Direct Displacement (SN2) Mechanism.- 5.3. Alternative Mechanistic Hypotheses.- 5.4. Carbonium Ions.- 5.5. Nucleophilicity.- 5.6. Leaving-Group Effects.- 5.7. Steric and Other Substituent Effects on Substitution and Ionization Rates.- 5.8. Stereochemistry of Nucleophilic Substitution.- 5.9. Secondary Kinetic Isotope Effects in Substitution Mechanisms.- 5.10. Neighboring-Group Participation.- 5.11. Carbonium Ion Rearrangements.- 5.12. Nonclassical Carbonium Ions and the Norbornyl Cation Problem.- 5.13. Synthetic Applications of Nucleophilic Substitution Reactions.- General References.- Problems.- 6. Polar Addition and Elimination Reactions.- 6.1. Addition of Hydrogen Halides to Alkenes.- 6.2. Acid-Catalyzed Hydration of Alkenes.- 6.3. Addition of Halogens.- 6.4. The E2, E1, and Elcb Mechanisms.- 6.5. Orientation Effects in Elimination Reactions.- 6.6. Stereochemistry of E2 Elimination Reactions.- 6.7. Dehydration of Alcohols.- 6.8. Eliminations Not Involving C-H Bonds.- General References.- Problems.- 7. Carbanions and Other Nucleophilic Carbon Species.- 7.1. Acidity of Hydrocarbons.- 7.2. Carbanions Stabilized by Functional Groups.- 7.3. Enols and Enamines.- General References.- Problems.- 8. Reactions of Carbonyl Compounds.- 8.1. Hydration and Addition of Alcohols to Aldehydes and Ketones.- 8.2. Addition-Elimination Reactions of Ketones and Aldehydes.- 8.3. Reactivity of Carbonyl Compounds toward Addition.- 8.4. Ester
Category: Science. ISBN: 9780306351167

Organic Quantum Chemistry Problems
This collection of examples of the application of quantum chemical methods in the study of various chemical problems (main ly in organic chemistry) arose from an arrangement of the ma terials used by the first of the authors in his lectures on organic quantum chemistry and chemical constitution, delivered since 1959 at the Science Department of the Charles University, as well as in courses of quantum chemistry and, finally, in his lectures on the fundamentals of quantum chemistry held in the years 1965-1967 at the universities of Wiirzburg, Groningen, and Giessen, and at the Technical University of Darmstadt. This collection is to be regarded as a supplement to exist ing textbooks on organic quantum chemistry. Whereas the situa tion is satisfactory as far as the number and the standard of text books and monographs in this field are concerned, this cannot be 1 4 said of the collections of examples. Although in some books - a certain number of examples are presented, we believe, in view of the great importance of numerical calculations, that a separate publication of examples would be useful. A similar subject has 5 been dealt with in the recently published book by A. and 0. Julg and in the first part of a trilogy to be published by Heilbronner 6 and Bock.
Category: Science. ISBN: 9780306305160

Essentials of Organic Chemistry
Essentials of Organic Chemistry is an accessible introduction to the subject for students of Pharmacy, Medicinal Chemistry and Biological Chemistry. Designed to provide a thorough grounding in fundamental chemical principles, the book focuses on key elements of organic chemistry and carefully chosen material is illustrated with the extensive use of pharmaceutical and biochemical examples. In order to establish links and similarities the book places prominence on principles and deductive reasoning with cross-referencing. This informal text also places the main emphasis on understanding and predicting reactivity rather than synthetic methodology as well as utilising a mechanism based layout and featuring annotated schemes to reduce the need for textual explanations. * tailored specifically to the needs of students of Pharmacy Medical Chemistry and Biological Chemistry * numerous pharmaceutical and biochemical examples * mechanism based layout * focus on principles and deductive reasoning This will be an invaluable reference for students of Pharmacy Medicinal and Biological Chemistry.
Category: Science. ISBN: 9780470016657

Introductory Organic Chemistry
Introductory Organic Chemistry provides a descriptive overview of organic chemistry and how modern organic chemistry is practiced. Organic compounds such as alkanes, cycloalkanes, alkenes, cycloalkenes, and alkynes are covered, along with aromatic hydrocarbons, compounds derived from water and hydrogen sulfide, and compounds derived from ammonia. This book also explores organic reaction mechanisms and describes the use of molecular spectroscopy in studying the chemical structure of organic complexes. This text consists of 15 chapters and begins with a discussion on some fundamental ideas about organic chemistry, from the electronic structure of atoms to molecular structure, molecular orbitals, hybridization of atomic orbitals in carbon, chemical equilibrium, enthalpy, and acids and bases. The chapters that follow focus on the compounds of carbon such as alkanes and cycloalkanes; benzene and other aromatic hydrocarbons; amines and other heterocyclic molecules; aldehydes and ketones; carboxylic acids and their derivatives; nucleic acids; amino acids; peptides; and proteins. The use of instrumentation methods in organic chemistry, particularly mass spectrometry and nuclear magnetic resonance spectroscopy, is also considered. An account of the mechanisms of an organic reaction is presented, paying particular attention to displacement and elimination reactions. This book concludes with a commentary on how most of the amino acids, sugars, heterocyclic molecules, and fatty acids necessary for life processes could have been formed on Earth. This book is intended for nonmajors taking an introductory organic chemistry course of two quarters or one semester in length.
Category: Science. ISBN: 9780122807503

Keynotes in Organic Chemistry
This concise and accessible book provides organic chemistry notes for students studying chemistry and related courses at undergraduate level, covering core organic chemistry in a format ideal for learning and rapid revision. The material is organised so that fundamental concepts are introduced early, then built on to provide an overview of the essentials of functional group chemistry and reactivity, leading the student to a solid understanding of the basics of organic chemistry. Graphical presentation of information is central to the book, to facilitate the rapid assimilation, understanding and recall of critical concepts, facts and definitions. Students wanting a comprehensive and accessible overview of organic chemistry to build the necessary foundations for a more detailed study will find this book an ideal source of the information they require. In addition, the structured presentation, highly graphical nature of the text and practice problems with outline answers will provide an invaluable framework and aid to revision for students preparing for examinations. Keynotes in Organic Chemistry is also a handy desk reference for advanced students, postgraduates and researchers. For this second edition the text has been completely revised and updated. Colour has been introduced to clarify aspects of reaction mechanisms, and new margin notes to emphasise the links between different topics. The number of problems have been doubled to approximately 100, and includes spectra interpretation problems. Each chapter now starts with diagrams to illustrate the key points, and ends with a list of key reactions and a worked example.
Category: Science. ISBN: 9781119999140
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